Basal cell carcinoma nodular C44.L

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Basal cell carcinoma nodular; nodular basal cell carcinoma

Definition
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Most common basal cell carcinoma (about 60% of the basal cell carcinomas that occur), characterised by nodular, exophytic growth with a tendency towards central ulceration.

Localization
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Almost exclusively on the head, especially the zygomatic arch, bridge of the nose, inner corner of the eye, auricle, capillitium.

Clinical features
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  • Initially small, skin-coloured, waxy, shiny, rough, painless nodule with fine telangiectasia covering the edge of the nodule. Slow growth, possibly formation of several aggregated nodules. Central depression and atrophy, finally ulceration. Formation of an ulcer with a (pearl-like) edge wall consisting of shiny papules, so-called ulcer rooting.
  • Some of the nodular BCCs have irregular pigmentation, whereby the pigment (melanin) may have brown or blue tones (depending on the location of the pigment accumulation, e.g. basal cell carcinoma, pigmented).

Histology
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Differential diagnosis
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Therapy
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Literature
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  1. Mc Cormack et al (1997) Differences in ages and body site distribution of the histological subtypes of basal cell carcinoma. Arch Dermatol 133: 593-596
  2. Peris K et al (2005) Imiquimod treatment of superficial and nodular basal cell carcinoma: 12-week open-label trial. Dermatol Surgery 31: 318-323

Disclaimer

Please ask your physician for a reliable diagnosis. This website is only meant as a reference.

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Last updated on: 29.10.2020