Basal cell carcinoma nodular C44.L

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 18.12.2020

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Synonym(s)

Basal cell carcinoma nodular; nodular basal cell carcinoma

Definition
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Most common basal cell carcinoma (about 60% of the basal cell carcinomas that occur), characterised by nodular, exophytic growth with a tendency towards central ulceration.

Localization
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Almost exclusively on the head, especially the zygomatic arch, bridge of the nose, inner corner of the eye, auricle, capillitium.

Clinical features
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  • Initially small, skin-coloured, waxy, shiny, coarse, painless nodule with fine telangiectasias covering the edge of the nodule. Slow growth, possibly formation of several aggregated nodules. Central depression and atrophy, finally ulceration. Development of an ulcer with a (pearly) marginal wall consisting of shiny papules, so-called ulcus rodens.
  • Some nodular BCCs have irregular pigmentation, whereby the pigment (melanin) can be brown or blue (depending on the location of the pigment accumulation, see also Basal cell carcinoma, pigmented).

Histology
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Differential diagnosis
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Therapy
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Literature
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  1. Mc Cormack et al (1997) Differences in ages and body site distribution of the histological subtypes of basal cell carcinoma. Arch Dermatol 133: 593-596
  2. Peris K et al (2005) Imiquimod treatment of superficial and nodular basal cell carcinoma: 12-week open-label trial. Dermatol Surgery 31: 318-323

Disclaimer

Please ask your physician for a reliable diagnosis. This website is only meant as a reference.

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Last updated on: 18.12.2020