Antiprotozoal agents

Author: Prof. Dr. med. Peter Altmeyer

All authors of this article

Last updated on: 29.10.2020

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Definition
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Medicines effective against protozoa, see Table 1.

Tables
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Overview of antiprotozoal agents and their indication

Pathogen

Active substance

amoebas

Acanthamoeba spp.

Amphotericin B, sulfonamides, for keratitis: Neomycin

Dientamoeba fragilis

possibly metronidazole

endolimax nana

no therapy necessary

entamoeba coli

no therapy necessary

histolytic entamoeba

Metronidazole

Negleria fowleri

Amphotericin B (possibly + rifampicin or miconazole)

Ciliates

Balantidium coli

tetracycline, metronidazole

Flagellates

Chocolomastix mesnii

possibly metronidazole

Giardia lamblia

Metronidazole

Leishmania braziliensis complex

Antimony preparations, pentamidine

Leishmania donovani complex

Antimony preparations, pentamidine

Leishmania tropica

Antimony preparations

vaginal trichomonas

Metronidazole

Trypanosoma br. gambiense, rhodiense I, II

Suramin or Pentamidine

Trypanosoma br. gambiense, rhodiense III

Melarsoprol

Trypanosoma cruzi

Nifurtimox

Sporozoen

Babesia spp.

Diamidine, clindamycin and/or quinine

Cryptosporidium spp.

Spiramycin

Plasmodium spp.

chloroquine, mefloquine, quinine, possibly primaquine

pneumocystis carinii

clindamycin/pentamidine or trimethoprim/sulfamethoxazole

Sarcocystis spp.

possibly sulfonamides

toxoplasma gondii

Sulphonamides, clindamycin or sulphonamides or pyrimethamine or spiramycin

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Last updated on: 29.10.2020