Nifurtimox
Definition
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Antiprotozoan agent, nitrofuran derivative.
Half-life
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3 h
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Indication
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Sleeping sickness.
Dosage and method of use
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- Adults: 2-2,5 mg/kg bw/6 hours for 3-4 months.
- Children: 4-6 mg/kg bw/6 hrs
Remember! The therapy should only be done under medical supervision!
Undesirable effects
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Fatigue, allergic reactions, gastrointestinal disorders, convulsions, headaches, paresthesias, polyneuritis, sleep disorders, dizziness, tremor.
Interactions
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Alcohol consumption can increase toxicity.
Contraindication
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Neurological or psychiatric diseases, alcoholism.
Preparations
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Lampit
Note(s)
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Not approved as a preparation in Germany (off-label use!)
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Prof. Dr. med. Peter Altmeyer