Hexachlorophen
Definition
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Phenol derivative, keratolytic.
Pharmacodynamics (Effect)
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Disinfection with primarily antimicrobial effect against gram-positive germs.
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Indication
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Cave! Today abandoned therapy principle!
Limited indication
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Breastfeeding.
Standard concentration
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Apply 0.1-1% in soaps, creams and ointments 1-2 times/day thinly to previously cleansed skin.
Undesirable effects
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Allergic reactions, potential teratogenicity, photosensitization, neurotoxicity (no large-scale application on damaged skin).
Contraindication
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Infants: Risk of serious or fatal poisoning, pregnancy.
Incompatibility
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Non-ionic surfactants (tweens) reduce the antimicrobial inhibitory effect of hexachlorophene.
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Prof. Dr. med. Peter Altmeyer