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The generation of an immune response by an antigen and subsequent antibody formation or the formation of specific T-lymphocytes in the sense of the immune response (see below epicutaneous test for type IV sensitization). In linguistic usage partly used synonymously with allergy. Active artificial sensitization by antigen tracking (e.g. vaccination). Type IV sensitisation plays a role in many eczematous skin diseases (see below: eczema, contact dermatitis, allergic). Their great socio-economic importance is expressed in the occupational disease No. 5101 of the Annex to the Ordinance on Occupational Diseases. S.u. Occupational disease of the skin.