Provocation test, nasal

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

NPT

Definition
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Method for recording a clinically current sensitization to inhaled allergens (e.g. house dust mite allergy). This makes it possible to differentiate it from a clinically silent sensitization.

Implementation
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Application of an aqueous allergen solution into a nostril, e.g. by means of a dosage aerosol or as a soaked cotton ball. In sensitized patients sneezing irritation and rhinorrhoea occur within a few minutes ( sensitization). Perform a negative control with the dilution solution before. Objective evaluation is performed by measuring the amount of secretion produced and the flow conditions in the nose (e.g. by active anterior rhinomanometry).

Note(s)
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Literature
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  1. Riechelmann H et al (2003) Application of the nasal provocation test on diseases of the upper airways. Position paper of the German Society for Allergology and Clinical Immunology (ENT Section) in cooperation with the Working Team for Clinical Immunology. Laryngorhinootology 82: 183-188

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Last updated on: 29.10.2020