Vasculopathies I99

General term for etiologically different vascular diseases. It is increasingly being used in the literature for primarily non-inflammatory vascular diseases that are associated with partial or complete occlusion of a vessel (e.g. livedo racemosa; see also livedovasculopathy). This definition distinguishes the term from the term " vasculitis" as an inflammatory vascular disease that affects the vascular system primarily or as part of an underlying disease.

• Vasculopathies of small vessels:
  • Coagulopathy of consumption
  • Purpura fulminans
  • Waterhouse-Friderichsen syndrome
  • Coumarin necrosis; thrombocytopenia, heparin-induced/HIT type II
  • Phospholipid antibody syndrome
  • Thrombotic thrombocytopenic purpura
  • Paroxysmal nocturnal haemoglobulinemia
  • Acroangiodermatitis
  • Livedovasculopathy
  • Lymphedema
  • Reactive angioendotheliomatosis
  • Cryoglobulinemic vasculitis (vasculopathies due to cold-dependent gelling or agglutiantion)
  • Drug-induced vasculopathies (minocycline, propythiouracil(ANCA-positive vasculitis), hydralazine, sulfasalazine, cocaine/levamisole/cocaine-inducedmidline destructive lesions, coumarin/coumarin necrosis, heparin/HIT type II)
  • Sickle cell anemia
• Vasculopathies of medium-sized vessels:
  • Livedo racemosa (livedovasculitis)
  • Calciphylaxis
  • Arterio-/Arteriolosclerosis
  • Cholesterol embolism
  • Embolia cutis medicamentosa.

1. Biedermann T et al. (2000) Livedoid vasculopathy in a patient with factor V mutation (Leiden). J Cutan Pathol 27: 410-412
2. Boyvat A et al. (2000) Livedoid vasculopathy associated with heterozygous protein C deficiency. Br J Dermatol 143: 840-842
3. Burg MR et al.(2025) Occlusive cutaneous vasculopathies: rare differential diagnoses. J Dtsch Dermatol Ges 23:487-506.
4. Cocuroccia B et al. (2002) Livedoid vasculopathy and skin ulcers in patients with inherited thrombophilia. Eur J Dermatol 12: 360-363
5. Grasland A et al. (2000) Livedoid vasculopathy (white atrophy) associated with anticardiolipin antibodies. Ann Med Interne (Paris) 151: 408-410
6. Hairston BR et al. (2003) Treatment of livedoid vasculopathy with low-molecular-weight heparin: report of 2 cases. Arch Dermatol 139: 987-990
7. Marzano AV et al. (2003) Widespread livedoid vasculopathy. Acta Derm Venereol 83: 457-460