Rutoside

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

CAS No:153-18-4; Rutin; Rutinum; Rutosidum

Definition
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Formerly known as vitamin P (factor P), flavonoid occurs naturally in numerous plants, such as buckwheat (Fagopyrum esculentum), rue (Ruta graveolens), hawthorn and Sophora japonica, the Japanese pagoda tree. The substance is moderately soluble in water (1g dissolves in about 8L of water), poorly soluble in ethanol, insoluble in ether.

Pharmacodynamics (Effect)
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Anti-edematous; the effect is not clearly proven.

Indication
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Chronic venous insufficiency, edema.

The active ingredient complex of rutoside (rutin), nicotiflorin and epicatechin acts as a phytoextract in rosacea anti-inflammatory (IL-1 inhibition) and inhibits the angiogenic factor VEGF.

Dosage and method of use
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3 times/day 50-100 mg p.o.

Preparations
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Cycloven forte N, Intradermi® Fluid N, Rutin Capsules

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Last updated on: 29.10.2020