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DefinitionThis section has been translated automatically.
Selective thrombin inhibitor. The heparin cofactor II does not act on AT-III. Its effect is enhanced by heparin and forms a complex with thrombin. The molecular weight is 65 kD.
The synthesis of the heparin cofactor II takes place in the liver, the plasma concentration is 9mg/l.
The half-life is 2.5 days. A lack of heparin cofactor II is associated with an increased risk of thrombosis.
LiteratureThis section has been translated automatically.
- HA Neumann (2014) The coagulation system. ABW-Wissenschaftsverlag GmbH Berlin p. 96.
Prof. Dr. med. Peter Altmeyer