Hierfür ist eine Anmeldung erforderlich. Bitte registrieren Sie sich bei uns oder melden Sie sich mit Ihren Zugangsdaten an.
DefinitionThis section has been translated automatically.
The coagulation system is antagonized by coagulation inhibitors. This prevents the coagulation from running out of control. It is a no less complicated system. Antagonists of the coagulation system or activators of the inhibitory coagulation system act on activators of the coagulation system.
| Clotting antagonist | Substrate |
| AntithrombinIII | Thrombin, Xa, IXa, VIIa, XIa, XIIa |
| heparin cofactor II | Thrombin |
| Protein C, Protein S | Va, VIIIa, PAI |
| TFPI | Xa, VIIa |
| alpha-1-antitrypsin | Thrombin, Xa, XIa, aPC, plasmin, kallikrein |
| C1 inhibitor | Kallikrein, plasmin, XIIa, XIa |
| alpha-2-macroglobulin | Thrombin, Xa, aPC, plasmin, kallikrein |
LiteratureThis section has been translated automatically.
- HA Neumann (2014) The coagulation system. ABW-Wissenschaftsverlag GmbH Berlin p. 94.
Prof. Dr. med. Peter Altmeyer