Ononidis radix

Authors: Prof. Dr. med. Peter Altmeyer, Prof. Dr. med. Martina Bacharach-Buhles

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Last updated on: 16.08.2025

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Synonym(s)

Hypocrite root; Radix ononidis; Uricaria root

Definition
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Ononidis radix, also known as Hauhechel root, is a drug that has been monographed by several commissions (Commission E, ESCOP) and is used in herbal medicinal products for the preventive treatment (flushing therapy) of inflammatory diseases of the urinary tract. The drug consists of whole or cut, dried roots of the plant.

HMPC monograph: Traditional-use: Increase in urine volume, irrigation of the urinary tract, for mild urinary tract complaints
ESCOP monograph: Irrigation of the urinary tract in inflammatory diseases, kidney gravel, urinary tract infections
Commission E-monograph: Irrigation in inflammatory diseases of the urinary tract, for the prevention and treatment of kidney gravel.

Empirical medicine: diuretic, for stone disease, gout and rheumatic complaints.

Ingredients
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Ononidis radix contains isoflavonoids (ononin), flavonoids, small amounts of essential oil, triterpenes (including alpha-onocerine).

Effects
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The hypocrite root has diuretic effects.

Field of application/use
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Ononidis radix is used for the preventive treatment of renal gravel and as a flushing therapy for inflammatory diseases of the urinary tract.

Dosage
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The usual daily dose is between 6 and 12 g and is used for infusions or other galenic preparations for ingestion.

Undesirable effects
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There are no known adverse effects.

Contraindication
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In case of existing edema due to impaired cardiac and renal activity should refrain from taking. Allergy to any of the ingredients, children under 12 years, no data for lactation and pregnancy.

Trade names
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As a monopreparation e.g. Ardeynephron®, Carito® mono capsules

Note(s)
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During a flushing therapy, care must be taken to ensure a sufficient fluid intake of at least 2 l/day.

Literature
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  1. Schilcher H (2016) Leitfaden Phytotherapie, Urban & Fischer Verlag, Munich, p. 155 f.
  2. https://arzneipflanzenlexikon.info/hauhechel.php
  3. https://www.ema.europa.eu/en/documents/herbal-monograph/final-community-herbal-monograph-ononis-spinosa-l-radix_en.pdf
  4. Blaschek W (2015) Wichtl tea drugs and phytopharmaceuticals. A handbook for practice. Wissenschaftliche Verlagsgesellschaft Munich. S 460-462