DefinitionThis section has been translated automatically.
Underground branched rhizome of the kava plant.
The drug, formerly specified in the German Drug Codex (DAC), may no longer be used medicinally.
HMPC: In 2017, it was decided that the risk exceeds the benefit due to liver damage.
ESCOP monograph: indicated liver toxic effect. Indication: anxiety, tension and restlessness of non-psychotic origin.
Commission E monograph: nervous states of anxiety, tension and restlessness.
Undesirable effectsThis section has been translated automatically.
Liver toxic, fatigue, weakness, loss of appetite and weight loss.
InteractionsThis section has been translated automatically.
Comatose states following the combination of kava with alprazolam, a diazepine derivative, have been described.
