Authors: Prof. Dr. med. Peter Altmeyer, Prof. Dr. med. Martina Bacharach-Buhles

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Last updated on: 29.10.2020

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Guo Wet al(2012) Imperatorin attenuates LPS-induced inflammation by suppressing NF-κB and MAPKs activation in RAW 264.7 macrophages. inflammation 35:1764-1772. Lin CL et al(2016) Imperatorin exerts antiallergic effects in Th2-mediated allergic asthma via induction of IL-10-producing regulatory T cells by modulating the function of dendritic cells. pharmacol res 110:111-121. raja SB et al(2010 Imperatorin a furocoumarin inhibits periplasmic Cu-Zn SOD of Shigella dysenteriae their by modulates its resistance towards phagocytosis during host pathogen interaction. biomed Pharmacother 65:560-568.

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Imperator is a naturally occurring furocoumarin. Chemically it is 8-isoamyleneoxypsoralen, a substance that is found in Urena lobata L. (Malvaceae), Angelica archangelica(angelica) and in Petroselinum crispum(parsley), Heracleum spp.

Imperatorin has antimicrobial, anti-inflammatory and anti-allergic properties. However, the substance is not used medicinally as a single substance, but only in the extracts of the various species of the plant. Medicinal plants.

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Angelica; Parsley;