Comfrey

Authors: Prof. Dr. med. Peter Altmeyer, Prof. Dr. med. Martina Bacharach-Buhles

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Last updated on: 09.10.2025

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Synonym(s)

Comfrey; Radix symphyti; symphyti radix; Symphyti radix/herba/folia

Definition
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Comfrey, Symphytum officinale, also known as common comfrey, is a deciduous, herbaceous plant belonging to the genus Symphytum in the family Boraginaceae. The plant is widespread throughout Europe and Asia, from Spain to China and Siberia. It grows to a height of 30-60 cm and produces a sturdy rhizome up to 50 cm long. The leaves are stalked, lanceolate and 20-25 cm in size, the bell-shaped flowers are white, yellowish-white, reddish-purple or purple or blue. It flowers from May to July.

The dried roots (comfrey root - Symphyti radix) and the dried herb (comfrey herb - Symphyti herba; Symphytum uplandicum) are used phytotherapeutically.

Cosmetics:

Symphytum officinale leaf powder (INCI)

Symphytum officinale leaf extract (INCI)

Symphytum officinale root extract (INCI)

Pharmacodynamics (Effect)
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Comfrey root has an anti-inflammatory, anti-swelling and anti-microbial effect and also promotes granulation and wound healing, as well as promoting callus formation. Improves blood circulation.

Spectrum of action
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Ingredients: allantoin, rosmarinic acid, mucilages and tannins, hydroxycinnamic acid, non-toxic pyrrolizidine alkaloids.

Indication
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External: Bruises, strains, sprains, muscle and joint pain due to blunt trauma

Internal: Systemic application is contraindicated due to the hepatotoxic and carcinogenic effect of the pyrrolizidine alkaloids contained in animal experiments.

Contraindication
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Use is not recommended during pregnancy, breastfeeding or in the presence of hypersensitivity to comfrey.

Comfrey preparations must also not be used in children under 3 years of age due to a lack of knowledge.

Preparations
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Arthrodynat® ointment, Hocura® spondylosis ointment, Kytta-Balsam®, Kytta-Plasma®f, Kytta-Schmerzsalbe®f, Syviman® N ointment, Traumaplant® pain cream, Zeel® T ointment

Literature
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  1. Araújo LU et al. (2012) In vivo wound healing effects of Symphytum officinale L. leaves extract in different topical formulations. Pharmacy 67:355-360.
  2. Barna M et al. (2012) Randomized double-blind study: wound-healing effects of a Symphytum herb extract cream (Symphytum xuplandicum Nyman) in children. Drug Research 62:285-289.
  3. Horinouchi CD et al. (2013) Botanical briefs: comfrey (Symphytum officinale).Cutis 91:225-228.
  4. Loew D (2012) in Beer A M et al [eds] Leitfaden Naturheilverfahren für die ärztliche Praxis, Urban und Fischer Verlag
  5. Pazyar N et al. (2014) Skin wound healing and phytomedicine: a review. Skin Pharmacol Physiol 27:303-310.
  6. Staiger C (2013) Comfrey root: from tradition to modern clinical trials. Wien Med Wochenschr 163(3-4):58-64.
  7. https://arzneipflanzenlexikon.info/beinwell.php
  8. Wenigmann M. (2017) Phytotherapy medicinal drugs, phytopharmaceuticals, application. Urban & Fischer, p.77-78
  9. https://www.ema.europa.eu/en/documents/herbal-monograph/final-european-union-herbal-monograph-symphytum-officinale-l-radix_en.pdf
  10. Blaschek W (2015) Wichtl tea drugs and phytopharmaceuticals. A handbook for practice. Wissenschaftliche Verlagsgesellschaft Munich. S 628-630