Cardiospermum halicacabum leaves

Authors: Prof. Dr. med. Peter Altmeyer, Prof. Dr. med. Martina Bacharach-Buhles

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Last updated on: 08.02.2022

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Synonym(s)

Balloon vine leaves; Balloon Vine Weed

Ingredients
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Effects
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Extracts from the monk's head plant (not to be confused with the "monk's head" Infundibilicybe geotropa - an edible fungus from the family of the knightly ones) have an anti-inflammatory, antipruriginous and antihelminthic effect.

Flavones and flavonol glycosides probably play a role in the anti-eczematous effect of Cardiospermum-Externa.

Clinical studies:In a clinical study, anti-inflammatory effects were shown comparable to the active ingredient bufexamac. In a double-blind placebo-controlled study in eczema patients, a positive effect could be demonstrated compared to placebo(LOE-A). Furthermore, several uncontrolled studies also exist in eczematous ( atopic eczema) skin diseases.

Field of application/use
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Application as ointments and tea preparations (compresses). Eczema, especially atopic dermatitis and pruritus.

Pregnancy/nursing period
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The use during pregnancy and lactation is not sufficiently documented and should not be used in this respect.

Trade names
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Cardiospermum® mother tincture, Dermaplant® ointment, Halicar® ointment,

Note(s)
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Cardiospermum-halicacabum seeds have a high oil content (about 33 %). It contains mainly long-chain fatty acids (lignococcinic acid, arachidic acid, oleic acid and stearic acid).

Literature
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  1. Huang MH et al,(2011) Antioxidant and anti-inflammatory properties of Cardiospermum halicacabum and its reference compounds ex vivo and in vivo. J Ethnopharmacol 133:743-750.
  2. Khunkitti W et al (2000) In vitro antifilarial activity of extracts of the medicinal plant Cardiospermum halicacabum against Brugia pahangi. J Helminthol 74:241-246
  3. Menichini F et al(2014) Chemical profiling and in vitro biological effects of Cardiospermum halicacabum L (Sapindaceae) aerial parts and seeds for applications in neurodegenerative disorders. J Enzymes Inhib Med Chem 29:677-685.
  4. Merklinger S et al (1995) Eczema treatment with Cardiospermum halicacabum. Cschr. for phythotherapy 16: 263-266
  5. Pratheeshkumar P et al,(2010) Cardiospermum halicacabum inhibits cyclophosphamide induced immunosupression and oxidative stress in mice and also regulates iNOS and COX-2 gene expression in LPS stimulated macrophages. Asian Pac J Cancer Prev 11:1245-1252.
  6. Reuter J et al (2010) Which plant for which skin disease? Part 1 JDDG 10: 788-796
  7. Sheeba MS et al.m(2009) Cardiospermum halicacabum ethanol extract inhibits LPS induced COX-2, TNF-alpha and iNOS expression, which is mediated by NF-kappaB regulation, in RAW264.7 cells. J Ethnopharmacol 124:39-44.
  8. Zalke AS et al (2013) Pharmacognostical evaluation of Cardiospermum halicacabum Linn. leaf and stem. Anc Sci Life 33:15-21.

Incoming links (2)

Balloon vine; Balloon vine weed;