Armoraciae rusticanae radix

Authors: Prof. Dr. med. Peter Altmeyer, Prof. Dr. med. Martina Bacharach-Buhles

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Last updated on: 02.07.2021

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Synonym(s)

Horseradish root; Pepper Root

Definition
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Fresh or dried roots harvested in spring or fall.

HMPC: not edited

But: In combination with Capuchin cress herb, indications proven by clinical studies (approval): Acute inflammatory diseases of the bronchi, sinuses and draining urinary tract.
Commission e-monograph: internal and external: catarrh of the respiratory tract,

internal: infections of the urinary tract; external: hyperaemic treatment of mild muscular pains.

Ingredients
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The glucosinolates gluconatusturtiin and sinigrin. Also asparagine, glutamine and arginine. When the root components are crushed, hydrolytic splitting by the enzyme myrosinase occurs. This process leads to the formation of volatile mustard oil (phenylethyl and allyl mustard oil).

Effects
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Antimicrobial, spasmolytic, hyperemic

Field of application/use
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Internal and external applications.

Indications: Catharrh of the airways, adjuvant against infections of the urinary tract; external applications for muscle pain

Dosage
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20g/day of fresh root, mostly available as medicinal specialities. External preparations with max. 2% mustard oil.

Contraindication
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Children <4 years, gastrointestinal ulcers, nephritides

Trade names
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A combination preparation with nasturtium - Angocin Anti-Infekt N® (3x4Tbl./day) - is available as a commercial preparation. For the prophylaxis of recurrent infection (3x2 tablets/day)

Literature
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  1. Albrecht U et al (2007) A randomised, double-blind, placebo-controlled trial of a herbal medicinal product containi g Tropaeoli majoris herba (Nasturtium) and Armoraciae rusticanae radix (Horseradish) for the prophylactic treatment of patients with chronically recurrent lower urinary tract infections. Curr Med Res Opin 23:2415-2422.
  2. Conrad A et al(2013) Broad spectrum antibacterial activity of a mixture of isothiocyanates from nasturtium (Tropaeoli majoris herba) and horseradish (Armoraciae rusticanae radix). Drug Res (Stuttgart)63:65-68.
  3. Conrad A et al (2006) In vitro study to evaluate the antibacterial activity of a combination of the haulm of nasturtium (Tropaeoli majoris herba) and of the roots of horseradish (Armoraciae rusticanae radix). Drug research 56:842-849.
  4. Fintelmann V et al (2012) Efficacy and safety of a combination herbal medicinal product containing Tropaeoli majoris herba and Armoraciae rusticanae radix for the prophylactic treatment of patients with respiratory tract diseases: a randomised, prospective, double-blind, placebo-controlled phase III trial. Curr Med Res Opin 28:1799-1807.