Aloin

Authors: Prof. Dr. med. Peter Altmeyer, Prof. Dr. med. Martina Bacharach-Buhles

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Last updated on: 28.07.2025

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Synonym(s)

Aloinum; Barbaloin

Definition
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Glycosidic anthrone derivative (1,8-dihydroxy-10-D-glucopyranosyl-9-anthrone), laxative main active ingredient of aloe. Aloin is soluble in water, ethanol and slightly soluble in ether.
The laxative effect of aloin is used medicinally for constipation (also in veterinary medicine). The anti-angiogenic and cytotoxic activities cause an antitumor effect. This also results in a local effect in psoriasis to reduce increased epithelial proliferation.

Dosage and method of use
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10-60mg /day p.o.

Literature
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  1. Syed TA et al (1996) Management of psoriasis with Aloe vera extract in a hydrophilic cream: a placebo-controlled, double-blind study* Trop Int Med Health 4: 505-509.
  2. Kessing R (2019) Herbal agents for topical application. The Private Physician 9: 42-43

Outgoing links (1)

Psoriasis vulgaris plaque type;