Images (4)

Vinca alkaloids

Author:Prof. Dr. med. Peter Altmeyer

All authors of this article

Last updated on: 04.03.2025

Dieser Artikel auf Deutsch

Synonym(s)

(e) vinca alkaloids; Vinca alkaloids

Requires free registration (medical professionals only)

Please login to access all articles, images, and functions.

Our content is available exclusively to medical professionals. If you have already registered, please login. If you haven't, you can register for free (medical professionals only).


Requires free registration (medical professionals only)

Please complete your registration to access all articles and images.

To gain access, you must complete your registration. You either haven't confirmed your e-mail address or we still need proof that you are a member of the medical profession.

Finish your registration now

DefinitionThis section has been translated automatically.

Group of approx. 70 partly semi-synthetically modified alkaloids from various periwinkle species. Vinca alkaloids inhibit cell division in metaphase and block DNA and RNA synthesis. The mitosis inhibitors vinblastine and vincristine, for example, are widely used as cytostatic agents in the chemotherapy of tumor patients.

Vinca alkaloids are derived from various periwinkle species belonging to the dogbane family, including the Madagascar periwinkle (Catharanthus roseus, syn. Vinca rosea) and the small periwinkle (Vinca minor).

Approval of preparations containing periwinkle was revoked by the Federal Health Office in 1987.

ClassificationThis section has been translated automatically.

  • Vinblastine and vincristine (dimeric alkaloids with cytostatic properties; nuclear spindle poisons)
  • Vincamine (antihypertensive and sedative; use in homeopathy, D1-D6)
  • Vindolin (antidiabetic effect)
  • Vinflunine, vinorelbine (semi-synthetic Vinca alkaloids).

LiteratureThis section has been translated automatically.

  1. Schilcher H (2015) Phytopharmaceuticals for tumor diseases. In: Guide to Phytotherapy. Urban and Fischer Publishing House Munich, S. 1019-1020

Authors

Last updated on: 04.03.2025

Author: Prof. Dr. med. Peter Altmeyer