DefinitionThis section has been translated automatically.
SCORE2/SCORE2-OP of the European Society of Cardiology (ESC) is the updated version of the calculation basis for estimating cardiovascular risk in healthy people aged 40 and over.
The risk of serious cardiovascular events within the next 10 years (10-year risk) is calculated on the basis of age, gender, blood pressure, cholesterol levels and smoking status.
The risk assessment serves as a basis for therapy decisions, e.g. lifestyle changes or additional drug therapy for the primary prevention of atherosclerosis and serious cardiovascular events. The indication for drug therapy exists at a 10-year risk of ≥10%.
For the indication for drug therapy to lower LDL-C, the risk assessment is also the basis for setting the target value.
SCORE2-OP is used for risk assessment for people aged 70 and over.
Risk assessment with SCORE2/SCORE2-OP is not suitable for people who already have cardiovascular disease or have suffered a serious vascular event. These people are already at high or very high risk and therefore the indication for drug therapy in addition to lifestyle changes. In this case, the target value for drug therapy to lower LDL-C should be ≤55 mg/dl (1.4 mmol/l).
Patients with diabetes mellitus are also already at high or very high risk, especially if they have had the disease for ≥10 years or already have end organ damage. Here too, the indication for drug therapy is given in addition to lifestyle changes with target LDL-C ≤55 mg/dl (1.4 mol/l).
Familial hypercholesterolemia is also not covered by SCORE2/SCORE-OP, as even in this case there is already a high or very high risk and the indication for drug therapy in combination with lifestyle measures is given.
ESC SCORE2/SCORE2-OP (APP for risk calculation).
