Löfgren's syndrome D86.8

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Acute Boeck's disease; Acute Sarcoidosis; Sarcoidosis acute

History
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Löfgren, 1946

Definition
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Acute early phase of sarcoidosis which occurs in about 10% of the patients.

Typical triad is:

  • Erythema nodosum
  • Bilateral swelling of the mediastinal lymph nodes
  • (ankle) arthritis

Also: fever, disturbance of the general condition, cough, increase of BSG. Hyp- or anergy in tuberculin test.

Manifestation
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Preferred among young women.

External therapy
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According to the erythema nodosum.

Internal therapy
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The value of systemic glucocorticoids (e.g. Decortin H initial 40-50 mg/day p.o., reduction by clinic for 12 months) is controversial. The long-term prognosis seems to be equally favourable with and without glucocorticoids.

Progression/forecast
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Favorable, spontaneous remission in over 95% of cases.

Literature
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  1. Petraityte J et al (2015) Acute form of sarcoidosis: Löfgren's syndrome. Act Dermatol 41: 152-154
  2. v. Stebut E (2015) Sarcoidosis. dermatologist 66: 549-563

Incoming links (2)

Boeck, m., acute; Tattoo;

Disclaimer

Please ask your physician for a reliable diagnosis. This website is only meant as a reference.

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Last updated on: 29.10.2020