Glutamattransporter

Last updated on: 18.12.2020

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Definition
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Glutamate transporters (Glut T) are found in neuronal and glial membranes. They rapidly remove glutamate from the extracellular space. In brain injury or disease, they often work in reverse and excess glutamate can accumulate outside the cells. This process causes calcium ions to enter cells through NMDA receptor channels, leading to neuronal damage and eventually cell death. This is called excitotoxicity.

Last updated on: 18.12.2020

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