Ena $$$

Author: Prof. Dr. med. Peter Altmeyer

All authors of this article

Last updated on: 08.05.2022

Dieser Artikel auf Deutsch

Synonym(s)

Extractable Nuclear Antigen; Extractable nuclear antigens

Definition
This section has been translated automatically.

Antibodies against nuclear and cytoplasmic components soluble at physiological salt concentrations:

Occurrence
This section has been translated automatically.

ENA antibodies are found particularly in collagenosis.

Note(s)
This section has been translated automatically.

The term ENA is historically explained by the extraction of nuclear, nucleolar or subcellular antigens from the nucleus or cytoplasm, respectively. Today, many "extractable antigens" are molecularly defined.

The naming has not been uniform so far. They were named either after the first letters of the patients in whom the respective antibody was first detected (e.g. Sm after Smith, Ro after Robert), after the biochemical structure of the antigen (RNP=ribonucleoprotein) or after the clinical picture in which this AK was first detected (SCL-70 = scleroderma).

Authors

Last updated on: 08.05.2022