Anti-mag antibodies

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Anti-myelin associated glycoprotein antibody

This section has been translated automatically.

Some forms of immune mediated polyneuropathy are associated with the occurrence of specific autoantibodies in serum.
Antibody formation can be partially
directed against a glycoprotein in the cell membrane of myelin sheaths
(MAG= myelin-associated glycoprotein).
Anti-MAG-Ak seems to be
involvedin the demyelination of the affected nerve tracts, especially in monoclonal IgM gammopathies,
and can be detected in serum at a frequency of more than 50%.

The chronic inflammatory demyelinating polyneuropathy (CIPD) is
accompaniedby slowly progressive,
symmetrically emphasized pareses and in individual cases shows an Ak formation against MAG.


Last updated on: 29.10.2020