Xanthomatosis papular normolipemic E78.29
Synonym(s)
Normolipemic papular xanthomatosis; Papular normolipemic xanthomatosis
Definition
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Generalized xanthomatosis with xanthomas up to smallerbsized without evidence of hyperlipidemia. The disease is classified in the xanthogranuloma family.
Manifestation
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Only for adults.
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Localization
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Face, trunk, rarely mucous membrane involvement.
Clinic
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2-15 mm large, yellowish, roundish, maculopapular efflorescences.
Histology
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Accumulation of fat-storing foam cells in the upper and middle corium; admixtures of lymphocytes, eosinophilic leukocytes and giant cells.
Electron microscopy: Detection of regularly structured "laminated bodies".
Differential diagnosis
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Therapy
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Spontaneous healing possible. If necessary, excision or curettage, ablation with theCO2 laser or with the help of cryosurgery, see below Xanthelasma.
Progression/forecast
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Variable course with tendency to spontaneous healing.
Literature
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- Breier F et al (2002) Papular xanthoma: a clinicopathological study of 10 cases. J Cutan Pathol 29: 200-206
- Bundino S et al (1988) Papular Xanthoma. Dermatologica 177: 382–385
- Caputo R et al (2003) Papular xanthoma associated with angiokeratoma of Fordyce: considerations on the nosography of this rare non-Langerhans cell histiocytoxanthomatosis. Dermatology 206: 165-168
- Sanchez RL et al (1985) Papular Xanthoma. Arch Dermatol 121: 626-631
- Yoshimura T et al (1994) Generalized normolipemic plane xanthomatosis associated with relapsing polychondritis. Acat Derm Venereol 74: 221-223
Recommended articles
Incoming links (3)
Hypertriglyceridemia familial; Xanthogranuloma necrobiotic with paraproteinemia; Xanthomas papulöse;Outgoing links (13)
Cryosurgery; Curettage; Dermis; Excision; Generalized eruptive histiocytosis; Juvenile xanthogranuloma; Laser; Reticulohistiocytosis multicenter; Xanthelasma; Xanthogranulomas (overview); ... Show allDisclaimer
Please ask your physician for a reliable diagnosis. This website is only meant as a reference.
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Prof. Dr. med. Peter Altmeyer