Vindesin
Definition
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Cytostatic drug, vinka alkaloid (see also vinblastine).
Half-life
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25 h.
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Indication
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Lymphatic leukemia, malignant lymphoma, malignant melanoma.
Dosage and method of use
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3 mg/m2 KO i.v. 1-2 times/week.
Undesirable effects
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BB changes, gastrointestinal disorders, subileus, liver or kidney damage, hyperuricemia, alopecia (see Alopecia medicamentosa), dermatitis, stomatitis, erythroderma, neurotoxic disorders, disorders of spermiogenesis and ovulation.
Preparations
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Eldisine
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Prof. Dr. med. Peter Altmeyer