Verrucosis polyneuropathica of the feet E14.4; E14.6

Author: Prof. Dr. med. Peter Altmeyer

All authors of this article

Last updated on: 07.08.2021

Dieser Artikel auf Deutsch

Synonym(s)

verrucous skin lesions of the feet in diabetic polyneuropathy; Verrucous skin lesions on the feet in diabetic neuropathy; VSLDN

History
This section has been translated automatically.

Gerbig and Hunziker, 1995

Definition
This section has been translated automatically.

Verrucous, benign epidermis proliferation of the feet, mostly occurring in patients with diabetes mellitus and polyneuropathy, but also in patients with polyneuropathies of other etiologies (e.g. alcohol toxic polyneuropathy).

Etiopathogenesis
This section has been translated automatically.

Unsolved. Discussed are chronic pressure or shear forces in existing neuropathy and angiopathy. Analogous clinical pictures are also observed in alcoholic polyneuropathy.

Manifestation
This section has been translated automatically.

Mainly occurring in old age.

Localization
This section has been translated automatically.

Toes and back of the foot.

Clinical features
This section has been translated automatically.

Particularly at pressure points, well defined, 2-5 cm large, skin-coloured to brown-blackish, wart-like, verrucous plaques with hyperkeratotic deposits can be found. Moistening is possible, especially with local infections. Occasionally recurrent pyoderma leads to an uncontrollable local infection, so that partial amputations are necessary.

Histology
This section has been translated automatically.

Pseudoepitheliomatous epidermal hyperplasia with pronounced hypergranulosis and isolated vacuolated keratinocytes. Focal papillomatosis. Ortho- and parahyperkeratosis. Dermis with thin round cell infiltrates. Mostly strong fibrosis.

Differential diagnosis
This section has been translated automatically.

General therapy
This section has been translated automatically.

Subtle adjustment of diabetes mellitus. Clarification of other causes of polyneuropathy and their therapy. Pressure relief. Ablative measures using a sharp curette or scalpel, if necessary after application of keratolytic external agents such as patches containing salicylic acid (guttaplast).

Literature
This section has been translated automatically.

  1. Gerbig AW, Hunziker T (1995) Verrucous skin lesions on the feet in diabetic neuropathy. Br J Dermatol 133: 1011-1012
  2. Sueki H et al (2004) Association of verrucous skin lesions and skin ulcers on the feet in patients with diabetic neuropathy. Clin Exp Dermatol 29: 247-253

Disclaimer

Please ask your physician for a reliable diagnosis. This website is only meant as a reference.

Authors

Last updated on: 07.08.2021