Ternidens deminutus infection B81.8

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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History
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Railliet and Henry, 1905

Definition
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Parasitic nematode infection by Ternidens deminutus.

Pathogen
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  • Ternidens deminutus (Nematode, nematode, family: Strongyloidea). Predominantly occurring in the intestine (ileum) of monkeys.
  • The adult worms reside in the ileum. The males are 9.5 mm long, the females 14 mm.
  • Eggs are excreted with the faeces of the infected host animals. On the ground, rhabditiform larvae initially grow from the eggs, which develop into infectious larvae in the form of filiaries.
  • Human infestation occurs when food contaminated with infectious filarial larvae is consumed.

Occurrence/Epidemiology
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  • Mainly occurring in monkeys (chimpanzees, gorillas, macaques, cercopithecus) in Africa, India, China, Indonesia, Thailand.
  • The infestation of humans has been described mainly in indigenous peoples of Africa.

Clinical features
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Mostly abdominal pain, fever, lymphadenopathy, eosinophilia. Intra-abdominal pseudotumours and helminthic abscesses with intestinal and, more rarely, extraintestinal involvement. Non-specific skin reactions are possible, especially maculopapular or urticarial exanthema and prurigo.

Diagnosis
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Microscopy of faeces: The eggs are similar to those of hookworms, but are larger at 85 x 40 µm.

Therapy
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In case of suspected intrabdominal pseudotumors or helminthic abscesses surgical intervention is inevitable.

Internal therapy
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Literature
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  1. Railliet & Henry A (1905) Un nouveau sclerotomien (Triodontophorus deminutus Nov sp.) parasite de 'I' homme. CR Soc Biol 58: 569-571
  2. Schindler AR, de Gruijter JM, et al (2005) Definition of genetic markers in nuclear ribosomal DNA for a neglected parasite of primates, Ternidens deminutus (Nematoda: Strongylida)--diagnostic and epidemiological implications. Parasitology 131: 539-546

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Last updated on: 29.10.2020