Sulfadiazine silver

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Definition
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Indication
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Prophylaxis of wound infections after burns, scalds and skin burns.

Notice!

Determine glucose-6-phosphate dehydrogenase before starting therapy!

Limited indication
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Pregnancy 1st trimenon, pregnancy last weeks (nucleus of the newborn), newborn, thyroid dysfunction.

Dosage and method of use
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Cream: Apply once/day in a thick layer or by means of sterile gauze.

Remember! Bubbles must be opened sterilely before and any cream residues must be removed with olive oil!

Standard concentration
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Cream: 1%.

Undesirable effects
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Allergic reactions, headaches, BB changes up to agranulocytosis, methaemoglobinaemia, hypoglycaemia, liver damage, crystalluria, arthralgias, erythema, gray discoloration of the skin (due to oxidation products), photosensitization, light dermatoses.

Interactions
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Crystalluria occurs with the administration of mandelic acid or methenamine.

Contraindication
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Hypersensitivity to sulfonamides, Z.n. erythema exsudativum multiforme, dermatitis exfoliativa generalisata subacuta or Lyell syndrome, glucose-6-phosphate dehydrogenase deficiency, hemoglobin abnormalities, severe liver and kidney dysfunction, leukopenia, acute hepatic porphyria.

Preparations
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Brandiazine, Flammazine, Urgotül S. Ag Grid Network

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Last updated on: 29.10.2020