Sulbactam/ampicillin
Synonym(s)
ampicillin/sulbactam
Definition
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Half-life
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1 h
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Indication
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Infections by ampicillin-sensitive and -resistant pathogens, if the resistance is based on the formation of β-lactamases
Limited indication
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Pregnancy, lactation, newborns and infants.
Dosage and method of use
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- Adults: 4-12 g/day i.v. or i.m. in 3-4 ED
- Children and infants from the 2nd week: 150 mg/kg bw/day i.v. in 3-4 doses i.v. or i.m.
Interactions
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Attenuation of the effect of aminoglycosides, metronidazole, noradrenaline, prednisolone, procaine, tetracyclines and thiopental, see also benzylpenicillin.
Contraindication
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Penicillin allergy, infectious mononucleosis and other viral infections (increased risk of exanthema!), lymphatic leukemia.
Preparations
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Unacid