Reye's syndrome G93.7
Synonym(s)
Hepatoencephalopathy; Reye-Morgan-Baral syndrome
History
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Reye, Morgan and Baral, 1963
Definition
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Rare acute encephalopathy, mostly occurring in children and adolescents, with cerebral edema and fine-drop fatty degeneration of the liver.
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Occurrence/Epidemiology
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Associated with varicella (15-40% of cases), influenza A and B, other febrile infections, especially when taking acetylsalicylic acid.
Etiopathogenesis
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Unknown, discussed are circulating toxins.
Progression/forecast
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40% lethality.
Literature
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- Caksen H et al (2001) A fatal case of Reye syndrome after varicella and ingestion of aspirin. J Dermatol 28: 286-287
- Kurup RK, Kurup PA (2003) The isoprenoid pathway and the pathogenesis of Reye's syndrome. Pediatr Pathol Mol Med 22: 159-170
- Reye RDK, Morgan, D, Baral J (1963) Encephalopathy and fatty degeneration of the viscera: a disease entity in childhood. Lancet 2: 749-752
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Disclaimer
Please ask your physician for a reliable diagnosis. This website is only meant as a reference.
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Prof. Dr. med. Peter Altmeyer