Reye's syndrome G93.7

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Hepatoencephalopathy; Reye-Morgan-Baral syndrome

History
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Reye, Morgan and Baral, 1963

Definition
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Rare acute encephalopathy, mostly occurring in children and adolescents, with cerebral edema and fine-drop fatty degeneration of the liver.

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Occurrence/Epidemiology
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Associated with varicella (15-40% of cases), influenza A and B, other febrile infections, especially when taking acetylsalicylic acid.

Etiopathogenesis
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Unknown, discussed are circulating toxins.

Progression/forecast
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40% lethality.

Literature
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  1. Caksen H et al (2001) A fatal case of Reye syndrome after varicella and ingestion of aspirin. J Dermatol 28: 286-287
  2. Kurup RK, Kurup PA (2003) The isoprenoid pathway and the pathogenesis of Reye's syndrome. Pediatr Pathol Mol Med 22: 159-170
  3. Reye RDK, Morgan, D, Baral J (1963) Encephalopathy and fatty degeneration of the viscera: a disease entity in childhood. Lancet 2: 749-752

Outgoing links (2)

Acetylsalicylic acid; Varicella;

Disclaimer

Please ask your physician for a reliable diagnosis. This website is only meant as a reference.

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Last updated on: 29.10.2020