DefinitionThis section has been translated automatically.
Intermittent occurrence of a mostly temporary, eruptive pustule in the area of already (longer) existing foci in psoriasis vulgaris. Pustule episodes can be accompanied by disturbances of the general condition up to fever.
Clinical featuresThis section has been translated automatically.
- Few to numerous, localized or disseminated, usually symmetrically distributed, scaly, variably elevated (infiltrated), red, sharply demarcated plaques of variable size (0.5cm to 10.0cm and >) and configuration (roundish or oval, map-like). Around the plaques varying numbers of white or gray-white pustules, varying in size, vulnerable and easily bursting, usually forming within a few days. In confluence, formation of weeping areas.
- Auspitz phenomenon is triggerable in the (pre-existing) psoriatic plaques.
- There is usually a high endogenous eruption pressure.
- Relapsing course with different relapse frequencies is characteristic.
- see also overview chapter Psoriasis
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LaboratoryThis section has been translated automatically.
Increased inflammation parameters (CRP, BSG); neutrophil leukocytosis;
HistologyThis section has been translated automatically.
S.u. Psoriasis vulgaris. Additionally spongiform pustules with neutrophil leucocytes.
External therapyThis section has been translated automatically.
- Initially, use dithranol only in low concentrations and increase the concentration very slowly (s.a. psoriasis vulgaris). Accompanying daily brine baths and tar baths are also possible (e.g. Balneum Hermal with tar). If necessary, use in combination with UVB. Increase UV doses very carefully. Avoid Dermatitis solaris under all circumstances.
- Alternative: Short-term external application of glucocorticoids, especially in case of fresh attacks. Pustules disappear after hours or days. After stopping the pustular flush, change to the classic external therapy scheme. Caution! Avoid irritating external agents!
Notice! The push activity is usually limited in time. Therefore the focus of the therapy has to be put on external measures!
Internal therapyThis section has been translated automatically.
Systemic therapy according to psoriasis vulgaris. In addition to retinoids, fumaric acid esters or methotrexate have also proved successful. In case of resistance to therapy, a combination of methotrexate and fumaric acid esters would be possible under strict control of laboratory values and immune status.
Progression/forecastThis section has been translated automatically.
The pustules disappear after hours or days.
Outgoing links (10)Dithranol; Fumaric acid ester; Glucocorticosteroids; Methotrexate; Peaking out phenomenon; Psoriasis (Übersicht); Psoriasis vulgaris; Pustule; Retinoids; Solar dermatitis;
Please ask your physician for a reliable diagnosis. This website is only meant as a reference.