Post-kala azar dermal leishmanoid B55.0

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Dermal Leishmanoid Post-Kala-Azar; Leishmaniasis dermal post-Kala-Azar; Leishmaniasis Post-Kala-Azar; leishmanoid dermal; Leishmanoid dermal post-Kala-Azar; Leishmanoid post-cala-azar dermal; PKDL; Post-kala-azar dermal leishmaniasis; Post-Kala-Azar dermal leishmaniasis; Post-Kala-Azar dermal leishmaniasis syndrome; Post-Kala-Azar dermal leishmanoids; Post-Kala Azar skin leishmanide; Skin leishmanide post-Kala-Azar

Definition
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Skin leishmaniasis as a late complication, which occurs in about 6% of those infected with visceral leishmaniasis (mainly men between the ages of 20 and 30), 1-3 years after visceral leishmaniasis. In India, about 20% of those infected with visceral leishmaniasis develop post-cal azar leishmanoid.

Localization
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Prefers face but also back and arms.

Clinical features
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Clinically, hypopigmented and reddened spots and nodules containing leishmania are found in hyperergic reactions.

In addition, light-provoked erythema, possibly leprosy-like image or image of systemic lupus erythematosus.

Such leishmanoids may also occur during the treatment of visceral leishmaniasis.

Laboratory
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Bluteosinophilia.

Therapy
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Treatment of the underlying disease as for visceral leishmaniasis. For single post-scale azar nodes: glucocorticoids such as triamcinolone acetonide (e.g. Volon A 10) intralesionally.

Literature
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  1. Antinori S et al (2007) Post-kala-azar dermal leishmaniasis as an immune reconstitution inflammatory syndrome in a patient with acquired immune deficiency syndrome. Br J Dermatol 157:1032-1036
  2. Barroso DH et al (2015) Post-kala-azar dermal leishmaniasis in two different clinical contexts. An Bras Dermatol 90 (3 Suppl 1):108-110
  3. Ramesh V et al (2015) Post-kala-azar dermal leishmaniasis in HIV-coinfected individuals: problems in diagnosis and treatment. Int J Dermatol 54:116-120

Disclaimer

Please ask your physician for a reliable diagnosis. This website is only meant as a reference.

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Last updated on: 29.10.2020