Oropouche fever A93.0

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 11.02.2021

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Synonym(s)

ORO

History
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Shope, 1962

Definition
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Dengue-like, self-limiting infectious disease transmitted by mosquitoes, caused by the Oropouche virus (arbovirosis), sporadic-endemic and sometimes occurring in large epidemics. It was named after the river Oropouche on Trinidad.

Pathogen
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  • Oropouche virus, family Bunyaviridae, representative of the Simbu serogroup.
  • Human-to-human transmission by the vectors Culex mosquitoes and Culicoides mosquitoes. Possible virus reservoirs are sloths, monkeys, birds.

Occurrence/Epidemiology
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Occurrence: Northern Brazil (cocoa cultivation), Southern Caribbean (Trinidad), Panama. The average duration of epidemics is about 6 months.

The first outbreak was described in 1950.

Clinical features
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Incubation period: 4-8 days. Acute onset of fever of 1-2 weeks duration. Fatigue, headache, myalgia and arthralgia, generalized lymphadenopathy, viral exanthema, aseptic meningitis.

Diagnosis
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  • Cultivation in cell cultures and in mice.
  • Serology (ELISA).

Differential diagnosis
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yellow fever; dengue fever; Mayaro infection; influenza

Therapy
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Supportive-symptomatic.

Progression/forecast
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Quick recovery. Long term immunity.

Prophylaxis
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Mosquito protection and control.

Disclaimer

Please ask your physician for a reliable diagnosis. This website is only meant as a reference.

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Last updated on: 11.02.2021