Nizatadine

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Definition
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Indication
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Diseases in the upper gastrointestinal tract where a reduction in gastric acid secretion is indicated, such as duodenal ulcers, benign gastric ulcers. Also for the prevention of recurrence of duodenal ulcers.

Pregnancy/nursing period
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Contraindicated during pregnancy and lactation.

Dosage and method of use
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  • 1 time per day in the evening 1 Kps. p.o. For mite Kps.: 1 time per day 2 Kps. (in the evening) or 2 times/day (morning and evening) 1 Kps. p.o.
  • ulcer recurrence prophylaxis: 1 cps. once/day in the evening 1 cps. p.o.
  • Patients with severe renal insufficiency (creatinine clearance less than 40 ml/min or serum creatinine concentration more than 2.5 mg/100 ml) and patients over 75 years of age with duodenal/ventricular ulcers: 1 cps once a day in the evening and 1 cps every 2 days if creatinine clearance is less than 20 ml/min.

Undesirable effects
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  • Occasionally: drowsiness, headache, dizziness, asthenia, chest pain, myalgia, insomnia, rhinitis, pharyngitis, cough, itching.
  • Rarely: hypersensitivity reactions (e.g. urticaria, exanthema, edematous swelling, angioedema of the lips or tongue, laryngeal edema, bronchospasm, eosinophilia), exfoliative dermatitis, sweating, anemia.

Interactions
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With simultaneous administration of very high doses of acetylsalicylic acid, the ASA level is increased.

Notice! Urobilogen tests with Multistix can be false positive!

Contraindication
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Pregnancy/nursing. Hypersensitivity to H2-receptor antagonists, malignant gastric ulcers, severe renal insufficiency. Caution in patients with bradycardic arrhythmias, as further slowing of the heart rhythm may occur.

Notice!

Do not use in children (insufficient data available)!

Preparations
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Nizax Lilly, Nizax Lilly mite

Outgoing links (1)

Antihistamines, h2-antagonists;

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Last updated on: 29.10.2020