Synonym(s)
DefinitionThis section has been translated automatically.
Nicotinic acid is a vitamin component of the vitamin B complex(vitamin B3). It is found in all vital cells and is stored in the liver. Nicotinic acid is a component of various coenzymes (NAD, NADP) and is therefore of essential importance for the metabolism of proteins, fats and carbohydrates.
Chemically, nicotinic acid is a heterocyclic organic compound, a pyridine-3-carboxylic acid with the molecular formula: C6H5NO2. It consists of a pyridine ring substituted with a carboxy group (-COOH). The isomers of nicotinic acid are picolinic acid and isonicotinic acid.
Nicotinic acid forms a white, crystalline powder that is hardly soluble in ethanol, water and acetone, but soluble in boiling water. Nicotinic acid is also soluble in alkaline solutions, forming salts.
EffectsThis section has been translated automatically.
When applied topically, the carboxylic acid leads to the release of prostaglandin D2 and thus to an increase in blood flow to the skin.
Cosmetics: Nicotinic acid compounds with fatty alcohols (ester formation) are mainly used in cosmetic formulations.
Prof. Dr. med. Peter Altmeyer