DefinitionThis section has been translated automatically.
The Blaschko lines of the following, possibly hemiplegic (unilateral epidermal nevus), or also bilateral localized epidermal nevus (epidermal nevus). The common epidermal nevus of the hard type (nevus verrucosus) is linear or arranged in a whirling pattern and characterized by a hard, warty, dirty-brown surface.
Occurrence/EpidemiologyThis section has been translated automatically.
Incidence is estimated at 1:1000 births.
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ManifestationThis section has been translated automatically.
Congenital or occurring in early childhood. 80% of nevi are diagnosable in the first year of life.
LocalizationThis section has been translated automatically.
Face, neck, torso, extremities.
Clinical featuresThis section has been translated automatically.
Bizarrely configured, often following a swirling line pattern (fountain pattern), linear or planar, often yellow or yellow-brown in infancy or toddlers, later brown or brown-black papules and/or plaques with a warty surface.
In the case of a flat cutaneous mosaic pattern, usually abrupt limitation to the midline (naevus verrucosus unius lateralis).
A bilateral, generalized distribution pattern is rarer (see fig.).
HistologyThis section has been translated automatically.
Differential diagnosisThis section has been translated automatically.
TherapyThis section has been translated automatically.
Progression/forecastThis section has been translated automatically.
The skin changes are usually only discreetly visible at the initial manifestation, inconspicuous, flat, surface-smooth. In the course of the years, continuously increasing, verrucous aspect.
Surprisingly, at times almost complete regression of an extensive verrucous nevus, with recurrence in the same location after several months, has been observed (see Fig.).
Note(s)This section has been translated automatically.
The epidermolytic epidermal nevus is a special form of the epidermal nevus of the hard type (= nevus verrucosus). Its histological peculiarity is the granular degeneration or acanthokeratolysis. Another special form is the inflammatory epidermal nevus(ILVEN).
Hamartomas of the skin in which the epidermis and/or skin appendages are altered (e.g. sebaceous nevus) are described as organoid epidermal nevi.
LiteratureThis section has been translated automatically.
- Kim R et al (2013) Verrucous epidermal nevus. Dermatol Online J 19: 20707
- Lapidoth M et al (2013) Treatment of verrucous epidermal nevus: experience with 71 cases. Dermatology 226:342-346
- Miranda LQ et al (2013) Analysis of mutations in the PIK3CA and FGFR3 genes in verrucous epidermal nevus. On Bras Dermatol 88(6 Suppl 1):36-38
- Rogers M et al (1989) Epidermal nevi and the epidermal nevus syndrome.
A review of 131 cases. J Am Acad Dermatol 20:476-88.
Incoming links (12)Angora hair nevus syndrome; Aplasia cutis congenita (overview); Degeneration, granular; Epidermal nevus; Hyperkeratotic nevus; Lateral nevus verrucosus unius lateralis; Naevus epidermal hard; Naevus, hard; Nevus durus; Nevus, hyperkeratotic; ... Show all
Outgoing links (14)Acanthosis; Blaschko lines; Degeneration, granular; Dermabrasion; Epidermal nevus (overview); Epigenetics; Excision; Ilven; Keratosis seborrhoeic (overview); Mosaic cutaneous; ... Show all
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