Multiple endocrine neoplasia 2A D44.8

Author: Prof. Dr. med. Peter Altmeyer

All authors of this article

Last updated on: 24.11.2022

Dieser Artikel auf Deutsch

Synonym(s)

MEN-2a; MEN-2a syndrome; MEN Type IIa; Multiple endocrine adenomatosis type IIa; sickle syndrome

History
This section has been translated automatically.

Sipple, 1961

Definition
This section has been translated automatically.

Disease belonging to the multiple endocrine neoplasms (OMIM 171400) with a combination of pheochromocytoma (possibly bilateral), medullary thyroid carcinoma, and possibly parathyroid adenoma, cutaneous lichen amyloidosus and Hirschprung's disease associated.

Etiopathogenesis
This section has been translated automatically.

Autosomal-dominantly inherited; mutation of the RET prooncogene, a gene coding for a transmembrane tyrosine kinase, which is mapped on chromosome 10q11.2

Literature
This section has been translated automatically.

  1. Breza J Jr et al (2018) Multiple endocrine neoplasia 2A (MEN 2A) syndrome. Bratisl Lek Listy119:120-125.

  2. Mathiesen JS et al (2022) Multiple endocrine neoplasia type 2: A review. Semin Cancer Biol 79:163-179

  3. Sipple JH (1961) The association of pheochromocytoma with carcinoma of the thyroid gland. Am J Med 31: 163-166
  4. Verga U et al (2003) Frequent association between MEN 2A and cutaneous lichen amyloidosis. Clin Endocrinol (Oxf) 59: 156-161.

Disclaimer

Please ask your physician for a reliable diagnosis. This website is only meant as a reference.

Authors

Last updated on: 24.11.2022