Mucinous nevus D48.1

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 08.09.2023

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Synonym(s)

Linear connective tissue naevus of the proteoglycan type; mucinous nevus

History
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Mc Grae, 1983

Definition
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Rare, congenital, mucinous connective tissue nevus.

Clinical features
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Isolated or multiple, yellowish-brownish or skin-coloured, mostly isolated, soft, elastic, symptomless papules, arranged in a linear or zosteriform fashion. Papules may confluent; formation of up to 5.0 cm large plaques with a smooth surface.

Histology
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Below an unchanged or slightly acanthotic epidermis, an uncoloured area that is almost unstructured in the HE section appears, which can take up almost the entire corium. In alcian blue staining, this area appears pale blue. Inflammatory infiltrates are completely absent.

Diagnosis
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Clinical presentation: The hamartoma genesis of the lesions is defined by the zosteriform or linear arrangement of the papules/plaques (cutaneous mosaic).

Differential diagnosis
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Therapy
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Not necessary. Surgical approach if lesions are cosmetically compromising.

Literature
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  1. Chang SE (2003) A case of congenital mucinous nevus: a connective tissue nevus of the proteoglycan type. Ped Dermatol 20: 229-231
  2. Lee MY et al (2018) Mucinous nevus. Ann Dermatol 30: 465-467.
  3. Mc Grae JD Jr (1983) Cutaneous mucinosis in infancy. A congenital and linear variant. Arch Dermatol 119: 272-273.

Disclaimer

Please ask your physician for a reliable diagnosis. This website is only meant as a reference.

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Last updated on: 08.09.2023