mSWAT

mSWAT is the acronym for: modified Severity of Illness Assessment Tool or Severity Weighting Assessment Tool (see also SWAT). SWAT is the acronym for: Severity of Illness Assessment Tool or Severity Weighting Assessment Tool. SWAT is a severity assessment tool and is typically used to assess the complexity or severity of clinical situations, especially in tumor patients in oncology or palliative care.

The mSWAT was originally introduced as a tool to track tumor burden in the skin of mycosis fungoides/Sézary syndrome.

The percentage of total body surface area (TBSA, %) is measured separately for patches, plaques and tumors in the 12 body regions, and each lesion type is multiplied by a number (patch = 1; plaque = 2; tumor = 4) to determine the mSWAT score (Olsen EA et al. 2007).

1. Olsen EA et al. (2007) Phase IIb multicenter trial of vorinostat in patients with persistent, progressive, or treatment refractory cutaneous T-cell lymphoma. J Clin Oncol 25:3109-3115.
2. Stevens SR et al. (2002) Quantifying skin disease burden in mycosis fungoides-type cutaneous T-cell lymphomas: the severity-weighted assessment tool (SWAT). Arch Dermatol 138:42-8