DefinitionThis section has been translated automatically.
Rare form of a primary herpes simplex infection, usually with infestation of the temporal lobe.
Clinical featuresThis section has been translated automatically.
Cephalea, vertigo, tinnitus aurium, meningismus.
DiagnosisThis section has been translated automatically.
Virus isolation from blood or cerebrospinal fluid.
TherapyThis section has been translated automatically.
In case of herpes simplex infection with suspected central involvement, immediate consultation of a neurologist. Increase or set the dosage of Aciclovir i.v. to 10 (max. 30) mg/kg bw/day. Alternatively Famciclovir p.o. (Famvir) 3 times/day 250 mg p.o. or Valaciclovir (Valtrex). In case of therapy failure Foscarnet (Foscavir Astra) 3 times/day 40-60 mg/kg bw/day i.v. in 500 ml NaCl solution over 2 hours.
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Prof. Dr. med. Peter Altmeyer