Keratoderma blenorrhagicum - Altmeyers Encyclopedia

Synonym(s)

keratodermia blenorrhagica; Keratodermia pustulosa in M. Reiter; Keratodermia pustulosa in Reiter syndrome

Definition
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Chronic recurrent pustulosis on the palms of the hands and soles of the feet as a partial symptom of urethro-conjunctival-synovial syndrome, or reactive arthritis (formerly Reiter's syndrome).

Clinic
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Circular hyperkeratotic, partly pustular or erosive foci, which soon change to planar erythematous and severely scaling changes and form lake-like pus foci.

Nail involvement with thickening and detachment.

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Histology
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Hyperkeratosis, parakeratosis, acanthosis, papillomatosis and spongiform pustules. More severe hyperkeratosis and parakeratosis than in pustular psoriasis generalisata.