Interferon beta
Synonym(s)
beta-Interferon; IFN β; IFN-β; INF beta; Interferon-beta; Interferon-β; β-Interferon
Definition
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Pharmacodynamics (Effect)
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Enhancement of the non-specific humoral defence in viral infections and enhancement of the expression of HLA class I antigens. Promotion of cellular cytotoxicity. Stimulation of CD8 cells.
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Indication
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Undifferentiated nasopharyngeal carcinoma, viral encephalitis, herpes zoster generalisatus and varicella in immunocompromised patients.
Limited indication
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Taking anticoagulant medication during therapy.
Dosage and method of use
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0,1 million IE/kg KG 3 times/week i.v.
Undesirable effects
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S.u. Interferon alfa-2a.
Interactions
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Like interferon alfa-2a, s. there.
Contraindication
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Pregnancy, lactation, children < 14 years, long-term therapy (> 5 weeks).
Preparations
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Fiblaferon
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Prof. Dr. med. Peter Altmeyer