HistoryThis section has been translated automatically.
Altman and Mehregan 1971
DefinitionThis section has been translated automatically.
Sharply defined mosaic dermatosis with eczematous, lichenoid or psoriatic papules or plaques with different surface textures, arranged in stripes (in the Blaschko lines)
These formations arranged according to the Blaschko line pattern (not sporotrichoid along the lymphatic channels or segmental) are highlighted by their arrangement, which is unusual for other macro patterns (see below Blaschko linear inflammatory dermatoses).
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Occurrence/EpidemiologyThis section has been translated automatically.
ManifestationThis section has been translated automatically.
Congenital or occurring in early childhood. In 75% of the patients the onset of the disease is <5 years. Rarely first appearance in adulthood. Very sporadic reports of familial occurrence have been made.
LocalizationThis section has been translated automatically.
Clinical featuresThis section has been translated automatically.
Sharply defined, linear or band-shaped red plaque(s) (or aggregated papules) with different (smoothlichenoid, eczematous or psoriasiform, verrucous) surface characteristics.
The lesions can be ichthyosiform, eczematous, psoriasiform, lichen planus-like or M. Darier-like in character.
Itching may be present. Arthritic changes may be associated with a psoriasiform ILVEN.
HistologyThis section has been translated automatically.
Very different pattern. As the ILVEN does not represent an "independent disease" but only an inflammatory dermatosis in a special (linear) arrangement (e.g. psoriasiform or eczematous ILVEN), the histological result will reflect a clinical correlate (see also Lichen striatus).
TherapyThis section has been translated automatically.
- Purely nurturing or anti-inflammatory therapy with weak or medium-strength glucocorticoids depending on the degree of inflammation, e.g. with 1% hydrocortisone emulsion, 0.1% triamcinolone acetonide cream R259, 0.1% methylprednisolone cream(e.g. Advantan), 0.1% hydrocortisone butyrate cream (e.g. Alfason). Individual successes were described with topical tretinoin, 5-fluorouracil and calcitriol (e.g. Silkis).
- In small flocks the excision should be discussed. Grinding or laser treatment of the skin is not very useful as recurrences occur almost regularly (explanation: the nevoid transformation does not only affect the epidermis but also the dermal structures).
Progression/forecastThis section has been translated automatically.
Sometimes slow magnification. Spontaneous (and surprising) healing is possible until adulthood.
LiteratureThis section has been translated automatically.
- Böhm M (2003) Successful treatment of inflammatory linear verrucous epidermal naevus with topical vitamin D3 (calcitriol). Br J Dermatol 148: 824-825
- Lee IW et al (1999) Inflammatory linear verrucous epidermal naevus arising on a burn scar. Acta Derm Venereol 79: 164-165
- Sidwell RU et al (2001) Pulsed dye laser treatment for inflammatory linear verrucous epidermal naevus. Br J Dermatol 144: 1267-1269
- Ulkur E et al (2005) Carbon dioxide laser therapy for an inflammatory linear verrucous epidermal nevus: a case report. Aesthetic Plast Surgery 28: 428-430
- Unna PG (1894) The histopathology of skin diseases. A. Hirschwald, Berlin
- Vissers WH et al (2004) Immunohistochemical differentiation between inflammatory linear verrucous epidermal nevus (ILVEN) and psoriasis. Eur J Dermatol 14: 216-220
Incoming links (9)Blaschko-linear inflammatory dermatoses; Blaschko lines; Inflammatory linear verrucous epidermal nevus; Inflammatory nevus linear verrucous epidermal; Lichen striatus; Mosaic cutaneous; Mosaic dermatosis acquired; Nevus verrucosus; Porokeratosis linearis unilateralis;
Outgoing links (12)Blaschko-linear inflammatory dermatoses; Blaschko lines; Calcitriol; Dyskeratosis follicularis; Excision; Fluorouracil; Glucorticosteroids topical; Hydrocortisone; Methylprednisolone; Mosaic cutaneous; ... Show all
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