IL1B Gene

Last updated on: 17.01.2024

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Definition
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The IL1B gene (IL1B stands for interleukin-1 beta) is a protein-coding gene located on chromosome 2q14.1. This gene and eight other genes of the interleukin-1 family form a cytokine gene cluster on chromosome 2.

Literature
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  1. Nakahara H et al (2003) Anti-interleukin-6 receptor antibody therapy reduces vascular endothelial growth factor production in rheumatoid arthritis. Arthritis Rheum 48:1521-1529.
  2. Tominaga K et al (2000) IL-12 synergizes with IL-18 or IL-1beta for IFN-gamma production from human T cells. Int Immunol 12:151-160.
  3. Van Damme J et al (1985) Homogeneous interferon-inducing 22K factor is related to endogenous pyrogen and interleukin-1. Nature 314:266-268.
  4. Xia S et al. (2021) Gasdermin D pore structure reveals preferential release of mature interleukin-1. Nature 593:607-611.

Last updated on: 17.01.2024