Jarisch-Herxheimer reaction; Reaction Jarisch-Herxheimer
HistoryThis section has been translated automatically.
Jarisch, 1895; Herxheimer, 1902
DefinitionThis section has been translated automatically.
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EtiopathogenesisThis section has been translated automatically.
Clinical featuresThis section has been translated automatically.
For syphilis: 2-6 hours after the first administration of penicillin, with feverish temperatures, flu-like symptoms, arthralgia, chills, headaches. In the rare late stage with an existing aortic aneurysm life-threatening (possible aortic aneurysm rupture due to sudden disintegration of the granulation tissue). No recurrence occurs with the following injections.
ProphylaxisThis section has been translated automatically.
Simultaneous administration of 25-50 mg prednisolone i.v. one hour before or with the initial administration of antibiotics.
Note(s)This section has been translated automatically.
S.a. Mazzotti reaction
LiteratureThis section has been translated automatically.
- Herxheimer K (1902) On a mercury reaction occurring in syphilitic patients. German medical weekly (Berlin) 28: 895-897
- Jarisch A (1895) Therapeutic trials for syphilis. Viennese medical weekly 45: 720-721
- Leblebicioglu H (2003) Jarisch-herxheimer reaction in leptospirosis. Eur J Clin Microbiol Infect Dis 22: 639
- Silberstein P (2002) A case of neurosyphilis with a florid Jarisch-Herxheimer reaction. J Clin Neurosci 9: 689-690
Incoming links (14)Benzathine benzylpenicillin; Herxheimer, karl; Jarisch, adolf; Jarisch-herxheimer reaction; Leptospirosis; Mazzotti reaction; Melarsoprol; Penicillin; Pentamidine diisethionate; Procaine benzylpenicillin; ... Show all
Outgoing links (10)Antibiotics; Antimycotics; Dermatophytes; Mazzotti reaction; Onchocerciasis; Prednisolone; Syphilis (overview); Tinea capitis profunda; Tinea corporis profunda; Treponema pallidum;
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