DefinitionThis section has been translated automatically.
Occurrence/EpidemiologyThis section has been translated automatically.
Precise data on incidence/prevalence are not known. However, it appears that an increase in prevalence has been demonstrated in recent years. Here, the "Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA)" seems to play a pathogenetic role (Demos M et al. 2012).
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EtiopathogenesisThis section has been translated automatically.
S. aureus has been shown to be the main risk of recurrent furunculosis (Demos M et al. 2012). In addition, there is a weakness of the immune system, e.g. as a result of metabolic diseases, diabetes mellitus, gastrointestinal disorders, chronic nephritis, diseases of the haematopoietic system with immune deficiency states and dysprotein anaemia. Tight-fitting, moisturising clothing can also be a cause.
DiagnosisThis section has been translated automatically.
TherapyThis section has been translated automatically.
External therapyThis section has been translated automatically.
In the intertrigines, disinfectant measures several times a day, e.g. polihexanide (Serasept, Prontoderm), quinolinol (e.g. quinosol or R042 ), cadexomer iodine (Iodosorb ointment), polyvidon iodine (Betaisodona), ethacridine lactate (e.g. 1% zinc paste containing ethacridine lactate); gauze strips). Local antibiosis of the nose with mupirocin (e.g. Turixin ointment).
Internal therapyThis section has been translated automatically.
In case of detection of Staphylococcuss aureus: Clindamycin: 2x 300mg p.o./day in combination with Rifampicin 2x300mg/day p.o. over 12 days.
Alternative: Trimethoprim/Sulfamethoxazole (TMP/SMX) 160/800 mg - 320/1600 mg 2x/day
Patients with fever receive trimethoprim/sulfamethoxazole 160/800 mg - 320/1600 mg 2x/day plus rifampicin 300 mg 2x/day for 10 days. Repeat the antibiotic cycle if necessary.
In case of signs of diabetes mellitus strict diabetes control.
ProphylaxisThis section has been translated automatically.
LiteratureThis section has been translated automatically.
- Demos M et al (2012) Recurrent furunculosis: a review of the literature. Br J Dermatol 167:725-732.
Incoming links (5)Boils; Ethacridine lactate monohydrate zinc paste 1% (nrf 11.7.); Felty syndrome; Folliculitis profunda (overview); Propicillin;
Outgoing links (7)Boils; Cadexomer iodine; Diabetes mellitus; Ethacridine lactate; Mupirocin; Polihexanide; Povidone-iodine;
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