Famotidine

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Definition
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Indication
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Duodenal ulcers, benign stomach ulcers, Zollinger-Ellison syndrome, recurrence prophylaxis of recurrent duodenal ulcers.

Pregnancy/nursing period
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Contraindicated.

Dosage and method of use
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  • Duodenal and benign gastric ulcers: once/day 40 mg p.o. in the evening before bedtime.
  • Zollinger-Ellison syndrome: 20 mg p.o. every 6 hours. Dose adjustment according to the extent of acid secretion.
  • Prophylaxis of recurrence of duodenal ulcers: once/day 20 mg p.o. in the evening before going to bed.

Undesirable effects
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Rare: ADRs such as headaches, dizziness, constipation or diarrhoea, dry mouth, nausea, vomiting, fatigue, pruritus, urticaria, increase in laboratory values (transaminases, g-GT, AP, bilirubin), intrahepatic cholestasis (jaundice), hypersensitivity reactions such as anaphylaxis, angioneurotic edema, bronchospasm and arthralgia, etc.

Contraindication
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Severe liver and kidney failure.

Notice!

Do not use on children (insufficient data available)!

Preparations
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Pepdul, Fadul, Famotidine-Ratiopharm

Outgoing links (1)

Antihistamines, h2-antagonists;

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Last updated on: 29.10.2020