Equine encephalitis, east american A83.2

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Eastern equine encephalitis; EEE; Equine East American encephalitis

History
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Webster and Wright, 1938

Definition
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Arbovirosis, caused by the Eastern Equine Encephalitis Virus (EEE virus), which can cause encephalitis in horses and humans

Pathogen
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  • East American equine encephalitis virus, genus Alphavirus, family Togaviridae.
  • The pathogens circulate between mosquitoes (Culex, Aedes and Coquillettidia and Culiseta species).
  • Epidemics in humans after epizootics, e.g. in horses.

Occurrence/Epidemiology
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  • Endemic-enzootic and epidemic-epizootic occurrence. Occurrence in East America, Gulf Coast to northern South America (Brazil) and the Caribbean.
  • Occurrence mainly in wet-hot summers.

Manifestation
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Children, adolescents and the elderly fall ill more seriously than adults. No sex preference.

Clinical features
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Sudden onset of fever, headache, dizziness, nausea, vomiting, neuro-psychological disorders as well as myalgias, severe encephalitis. Generalized viral exanthema rarely occurs.

Diagnosis
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Virus isolation. Antigen ELISA test.

Differential diagnosis
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Viral and bacterial encephalitis of other genesis.

Complication(s)
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Neurological defect healing, especially in children (infants and toddlers).

Therapy
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Symptomatic.

Progression/forecast
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  • Severe arbovirus encephalitis with a lethality between 50-75%.
  • Healing with severe neurological residual conditions.

Prophylaxis
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  • Mosquito control and protection.
  • Formalin-inactivated vaccines for risk groups and for horses.

Literature
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  1. Webster LT, Wright FH (1938) Recovery of Eastern Equine Encephalomyelitis Virus from Brain Tissue of Human case of Encephaltitis in Masachusetts. Science 88: 305-306

Outgoing links (1)

Virus exanthema (overview);

Disclaimer

Please ask your physician for a reliable diagnosis. This website is only meant as a reference.

Authors

Last updated on: 29.10.2020