Encephalitis, murray's valley encephalitis A83.4
Synonym(s)
Murray valley encephalitis; MVE
Definition
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Arbovirosis (endemic zooanthropoonosis), which is caused by the Murray Valley encephalitis virus.
Pathogen
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- Murray valley encephalitis virus, belonging to the Flaviviridae.
- Enzoonosis between mosquitoes (Culex species) and water birds (herons, pelicans), possibly also in kangaroos and rabbits.
- Horses and pigs only fall ill inapparently. Man is only a host by chance.
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Occurrence/Epidemiology
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- Occurrence in Australia and Papua New Guinea.
- Epidemics after rainfall.
Clinic
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- Blande courses, encephalitis and progressive brain decay are possible.
- Flu-like clinical picture with fever, chills, fatigue, headaches, nausea and vomiting.
- Skin changes are rare. Occasionally parainfectious viral exanthema occurs.
- Infection of the central nervous system: encephalitis with clouding of consciousness, seizures, reflex disorders, paresis and meningitis signs.
- In children threat of fudroyant courses.
Diagnosis
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- Virus isolation (brain).
- ELISA: Cross reactions with other flaviviruses (especially Kunjin virus) have to be considered.
Differential diagnosis
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Other viral and bacterial encephalitides, especially Japanese Encephalitis
Complication(s)(associated diseases
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Progressive brain decay. Lethal course.
Therapy
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Symptomatic.
Prophylaxis
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- Mosquito control and protection.
Literature
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- Mackenzie JS, Barrett AD, Deubel V (2002) The Japanese encephalitis serological group of flaviviruses: a brief introduction to the group. Curr Top Microbiol Immunol. 267: 1-10
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Disclaimer
Please ask your physician for a reliable diagnosis. This website is only meant as a reference.
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Prof. Dr. med. Peter Altmeyer